منابع مشابه
CALL FOR PAPERS MicroRNA and Tissue Injury MicroRNAs in skin and wound healing
Banerjee J, Chan YC, Sen CK. MicroRNAs in skin and wound healing. Physiol Genomics 43: 543–556, 2011. First published October 19, 2010; doi:10.1152/physiolgenomics.00157.2010.—MicroRNAs (miRNAs) are small endogenous RNA molecules 22 nt in length. miRNAs are capable of posttranscriptional gene regulation by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation or suppressio...
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INTRODUCTION Leptin, a 16 kDa anti-obesity hormone, exhibits various physiological properties. Interestingly, skin wound healing was proven to delay in leptin-deficient ob/ob mice. However, little is known on the mechanisms of this phenomenon. In this study, we attempted to elucidate a role of leptin in wound healing of skin. METHODS Immunohistochemical analysis was performed to confirm the e...
متن کاملSkin Function and Wound Healing Physiology
Regular evaluation and the setting of goals is essential to monitor the progress of the patient and their wound.To do this, is important to understand the physiology of the skin and the way normal wound healing progresses in order to plan and provide effective wound management. This article describes the structure and function of the skin and outlines the four normal phases of healing. SKIN FUN...
متن کاملMechanoregulation of Wound Healing and Skin Homeostasis
Basic and clinical studies on mechanobiology of cells and tissues point to the importance of mechanical forces in the process of skin regeneration and wound healing. These studies result in the development of new therapies that use mechanical force which supports effective healing. A better understanding of mechanobiology will make it possible to develop biomaterials with appropriate physical a...
متن کاملCirculating MicroRNAs Link Inflammation to Impaired Wound Healing in Diabetes.
S oon after their discovery in 1993, it became clear that microRNAs (miRs) regulate virtually all cellular processes. 1 Since then, many miRs have been described to coordinate gene expression programs in the context of cardiovascular disease, including diabetes mellitus. 2,3 MiRs usually perform their duties intracellularly, but interest in extracellular miRs as biomarkers or intercellular mess...
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ژورنال
عنوان ژورنال: Physiological Genomics
سال: 2011
ISSN: 1094-8341,1531-2267
DOI: 10.1152/physiolgenomics.00157.2010